The curvature of a surface determines the migration behavior of biological cells. They preferentially move along valleys or grooves while avoiding ridges. These findings, published in the journal ...

Traditional electrotaxis assays place electrodes directly into the cell culture medium, which inevitably drives current through the sample.

A new study integrated mathematical modeling with advanced imaging to discover that the physical shape of the fruit fly egg chamber, combined with chemical signals, significantly influences how cells ...

Evaluation of the hedgehog signaling pathway as a therapeutic target for dendritic cell-based immunotherapy against patients with cancer. Background: Activated fibroblasts in the stroma of epithelial ...

Figure 10: Biochemical effects of PCAIs on cancer cells. PCAIs-treated cancer cells show the depletion of the monomeric G-proteins RAC1 and RHOA. MAPK and PI3K/AKT signaling pathways are activated ...