Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists—so far. A new multi-chamber organoid ...

In the left part can be seen multi-omics analysis suggested some proteins (histone / non-histone), protein lactylation, and genes change significantly at different developmental stages (1 w [week], 6 ...

Heart disease remains the leading cause of death worldwide, yet progress in understanding and treating cardiac disorders is limited by the shortcomings of existing experimental models. Traditional ...

A recent Nature study uses a combination of single-cell ribonucleic acid (scRNA)-sequencing and high-resolution multiplexed error-robust fluorescence in situ hybridization (MERFISH) to better ...